OBSERVATION LINES
HECTARES OF PARCELLING
INTERNATIONAL PARTNERSHIPS
ANNUAL TONS OF CERTIFIED VARIETIES
Since the beginning of the domestication of the plants, two historical moments have revolutionized this process, allowing the obtaining of plant material that has better responded to the requirements, as the historical course of the farmer has progressed. The first of these two moments occurs at the beginning of the century, when we realized the importance of the ideas of Gregor Johann Mendel (Experiments on plant hybrids, published in the journal of the Natural History Society of Brno in 1866). In 1900, his work was rediscovered by Hugo de Vries, Carl Correns and Erich von Tschermak. Ronald Fisher in 1918 used the Mendelian theory as the basis for modern synthesis in evolutionary biology. What could have been a vision of the phenotype was actually the end result of a complex biological process still unknown, but which was soon revealed.
To pave the way for the understanding of which biological processes were at the base of the genetic differences between the different species, or between different individuals of the same species, were two researchers: the American James Watson and the British Francis Crick who, in 1953, presented in the magazine Nature what is now known as the first accurate model of DNA structure: that of the double helix. This represents the second fundamental historical moment that will profoundly mark the evolution of modern genetics. In an important presentation in 1957, Crick proposed the central dogma of molecular biology, which establishes the relationships between DNA, RNA and proteins. The final confirmation of the replication mechanism based on the double helix structure was provided in 1958 by the Meselson-Stahl experiment. A subsequent work by Crick showed how the genetic code was based on triplets of non-overlapping bases, allowing Har Gobind Khorana, Robert Holley and Marshall Warren Nirenberg to decipher it. These discoveries are the basis of modern molecular biology.
Since 1953, DNA research has made great strides. Today we are no longer discussing the established DNA structure, but what a particular piece of DNA does, how our history is written inside this molecule, the relationship between DNA and disease, and the use of this molecule in those that new biotechnologies are defined. We must not forget, however, a third key step that allowed us to read and decipher the enormous sequence of nitrogenous bases that constitute the genetic information of every living individual: the discovery of the polymerase chain reaction (Polymerase Chain Reaction or PCR ), a technique that has revolutionized the world of chemistry and genetics, allowing the in vitro amplification of DNA fragments with innumerable applications in the medical, agricultural and animal fields. This discovery was made in 1983 by Kary Banks Mullis and earned him the Nobel Prize in chemistry in 1993. If today molecular technology has allowed us to sequentially different genomes of different living species, including humans, and to identify several genes of interest, both human, animal and plant, a big thank you goes to this man.